0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

Hypoalbuminemia in Hospitalized Patients With Community-Acquired Pneumonia

Jonas U. Hedlund, MD; Lars-Olof Hansson, MD; Åke B. Örtqvist, MD, PhD
Arch Intern Med. 1995;155(13):1438-1442. doi:10.1001/archinte.1995.00430130132014.
Text Size: A A A
Published online

Background:  Hypoalbuminemic patients admitted to the hospital for community-acquired pneumonia have increased mortality and morbidity. The aim of this study was to investigate the reasons for hypoalbuminemia in these patients.

Methods:  During a 12-month period, all patients aged 50 to 85 years (with the exception of immunocompromised patients) with community-acquired pneumonia who were admitted to the Department of Infectious Diseases at Danderyd Hospital, Stockholm, Sweden, were included in a prospective study. The population studied consisted of 97 patients with a mean age of 69.6 years. The patients' nutritional status, including weight, history of weight loss, body mass index, and triceps skinfold thickness, was assessed on admission, as well as at two follow-up visits 8 weeks and 6 months after discharge from the hospital. Blood samples were drawn on admission, during the time in the hospital, and at the follow-up visits. Laboratory tests performed included the following: plasma proteins, albumin, transthyretin and transferrin, α1-antitrypsin, orosomucoid, haptoglobin, C-reactive protein, and interleukin-6.

Results:  No correlation was found between the serum albumin levels and the nutritional measurements. The serum albumin levels correlated positively with the transthyretin and transferrin levels, and inversely with the acute-phase proteins.

Conclusions:  The inflammatory reaction is the main reason for depressed serum albumin levels in elderly patients with pneumonia. The study results do not support the use of nutritional supplementation to alter the clinical outcome in these patients.(Arch Intern Med. 1995;155:1438-1442)

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Web of Science® Times Cited: 29

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();