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Epidural Abscess due to Acute Brucella melitensis Infection

Juan Pérez-Calvo, MD; Carlos Matamala; Isabel Sanjoaquin; Ana Rodriguez-Benavente; Fernando Ruiz-Laiglesia, MD; José Bueno-Gomez, MD
Arch Intern Med. 1994;154(12):1410. doi:10.1001/archinte.1994.00420120142015.
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We have read with interest the article on epidural spinal abscess by Maslen et al.1 The need to start a rapid course of treatment is imperative to prevent irreversible complications. Therefore, we thought that it would be useful to provide the following two case reports of epidural spinal abscess, both produced by systemic Brucella melitensis infection, an organism that did not appear in the list of causal agents reported by the aforementioned authors and whose tropism in the central nervous system is well known.

Report of Cases. Case 1.  A 62-year-old man was admitted with fever, headache, and lumbar pain irradiating along the SI root, a week after these symptoms had developed. A rose bengal test revealed positive results, as did the Brucella seroagglutination test (a titer of 1:5120). Three blood culture specimens yielded B melitensis. Cerebrospinal fluid agglutination was positive at a titer of 1:40. Spondylitis (L5-S1) was


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