0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

Meta-analysis Pitfalls: Deep Venous Thrombosis in Patients Undergoing Elective Hip Surgery-Reply

David N. Mohr, MD; Marc D. Silverstein, MD
Arch Intern Med. 1994;154(11):1296. doi:10.1001/archinte.1994.00420110143019.
Text Size: A A A
Published online

Doctor Potyk raises a concern that although inclusion criteria for studies included in the meta-analysis of deep venous thrombosis prophylaxis were appropriate, some studies using different doses or products of a prophylactic agent were grouped inappropriately. He references data that suggest these differences result in different prophylactic efficacy.

Although we do not dispute that delaying warfarin until the fifth day postoperatively or using 1 mg of warfarin both preoperatively and postoperatively may be inadequate dose schedules, the two warfarin-only studies that we included in our meta-analysis did not use these dose schedules. We, therefore, did not combine studies in which dosing differences are related to differences in efficacy. For external pneumatic compression and low-molecularweight heparin, he states the concern is only theoretic.

Meta-analysis is the systematic overview of individual studies to combine results and integrate the findings to draw conclusions about the effectiveness of therapeutic interventions.1,2 Meta-analysis uses explicit

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();