Hepatitis E seems to be responsible for most epidemics of non-A, non-B hepatitis in developing countries. While hepatitis E is not endemic in the United States, it should be considered in the differential diagnosis of the traveler with non-A, non-B hepatitis. we describe a patient with acute hepatitis E, confirmed by serologic testing, after recently returning from India and discuss current knowledge about the pathogenesis, clinical features, and diagnosis of hepatitis E.
(Arch Intern Med. 1993;153:773-775)