Diuretic Therapy on Sexual Function

Tsung O. Cheng, MD
Arch Intern Med. 1992;152(5):1097. doi:10.1001/archinte.1992.00400170159035.
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To the Editor. —  The recent article on the impact of diuretic therapy on sexual function by Chang et al1 is extremely important and timely. In casual conversations with my colleagues at a recent national medical meeting, I was surprised to find that although almost every physician knew about the unfavorable side effect of sexual dysfunction associated with the use of β-blockers, fewer seemed to be aware of similar undesirable effects following the use of diuretics. Furthermore, although most of the physicians whom I queried were familiar with the Medical Research Council's2 findings that the use of propranolol was associated with withdrawal from treatment due to sexual impotence, very few were aware of the fact that the withdrawal for the group receiving propranolol treatment was actually at a lower frequency than for the group receiving thiazide therapy.Since thiazide diuretics are the most commonly prescribed antihypertensive agent in


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