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Long-term Glycemic Control in Patients With Type II Diabetes

Thomas A. Wadden, PhD
Arch Intern Med. 1991;151(7):1269-1270. doi:10.1001/archinte.1991.00400070047001.
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The excellent study by Wing and colleagues in this issue of the Archives1 will be of interest to readers for the following reasons: (1) its demonstration of long-term glycemic control in patients with type II diabetes; (2) its comparison of two very popular but radically different approaches to weight control; and (3) its implicit recognition of the pressing need for research on the maintenance of weight loss.

Numerous studies have shown that caloric restriction and weight loss are associated with short-term improvements in fasting blood sugar (FBS) in type II diabetics.2 The exciting finding of the present study, however, is the demonstration that brief treatment by a very-low-calorie diet (VLCD) was associated with significant improvements in glycemic control fully 1 year after treatment and despite significant weight regain. Treatment by a conventional 4184- to 6276-kJ/d diet did not confer similar long-term benefits, despite the fact that weight losses


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