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Nontyphoidal Salmonella Pleuropulmonary Infections

Maureen B. Murdoch, MD; Lance R. Peterson, MD
Arch Intern Med. 1991;151(1):196. doi:10.1001/archinte.1991.00400010178029.
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To the Editor.——  We read with interest the recent report1 concerning pleuropulmonary infections due to nontyphoid Salmonella. The review contained only one case of empyema in 11 patients. We would like to report one additional case of Salmonella empyema.A 72-year-old man presented with splenomegaly and myelodysplastic syndrome with a 4-month history of shortness of breath, progressive weakness, weight loss, and syncope. Chest roentgenogram revealed opacification of the left hemidiaphragm. Thoracentesis revealed an empyema, and culture samples yielded Salmonella enteritidis. An extensive evaluation failed to reveal a source of the Salmonella isolated from the empyema. The patient was treated with chest tube drainage and ciprofloxacin, 750 mg orally twice daily. He defervesced and noted improvement in his symptoms 48 hours after antibiotics had been started. After 2 weeks, the patient was discharged home to complete a 4-week course of ciprofloxacin. He initially did well, gained weight, and his frequent

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