We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Preoperative Aspirin Therapy and Reoperation for Bleeding After Coronary Artery Bypass Surgery

G. Bashein, MD, PhD; Michael L. Nessly; Andrew L. Rice, MD; Richard B. Counts, MD; Gregory A. Misbach, MD
Arch Intern Med. 1991;151(1):89-93. doi:10.1001/archinte.1991.00400010105014.
Text Size: A A A
Published online


We performed a case-control study to estimate the relative risk of reoperation for bleeding in coronary artery bypass graft patients who had taken aspirin within the 7 days preceding sur gery. Comparison of 90 cases of reoperation with 180 matched control subjects gave an estimated odds ratio for reoperation of 1082 (95% confidence interval, 1.23 to 3.32). Although their preop erative coagulation values were similar, cases used significantly more whole blood (cases, 9.5 + 5.2 units; control subjects, 3.0 + 2.0 units; median + interquartile range), packed red blood cells (cases, 2.1 + 4.0 units; control subjects, 0.9 +- 2.0 units), and platelets (cases, 12.2 +- 12.0 units; control subjects, 2.9 +- 4.0 units) than control subjects. Cases had intensive care unit stays of 4.7 +- 5.7 days (mean SD) vs 2.1 1.9 days for control subjects and postoperative hospitalizations of 10.9 +- 8.2 days vs 7.0 +- 3.2 days for control subjects. We conclude that aspirin exposure within 7 days before coronary bypass surgery is asso ciated with an increased rate of reoperation for bleeding and that reoperation is associated with large increases in transfusion requirements and intensive care unit and hospital stays.

(Arch Intern Med. 1991;151:89-93)


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

71 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.