We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Phenytoin Monitoring in Nursing Home Patients-Reply

Arch Intern Med. 1990;150(9):1971-1974. doi:10.1001/archinte.1990.00390200145034.
Text Size: A A A
Published online


In Reply.—We would like to reassure Drs Courtney and Falbe that it is not the policy of our nursing home to measure serum phenytoin concentrations at least monthly in every patient. The large number of the measurements was the result of an ongoing larger study looking at drug-drug interactions in nursing home patients. The indications for measuring serum phenytoin levels have been elegantly discussed by Troupin, 1 and we had commented on those in our "Comment" section. Whether these indications are applicable to frail nursing home patients cannot be dogmatically stated. This was precisely the question we wanted to address, since previous studies are done in younger patients.2,3

The lack of clinically apparent toxicity is not surprising considering the difficulty in recognizing phenytoin toxicity in a patient population with a high prevalence of neurologic deficits and alterations in mental status.4 Availability of serum levels of phenytoin may


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.