In Reply. — I appreciate Krane's interest in the subject of microscopic hematuria. My study was essentially stimulated by my lack of discovery of bladder neoplasms in female patients whom I evaluated for asymptomatic microscopic hematuria. I wish to make it clear that all of the subjects of the study were evaluated by their internists prior to being referred to me. None of these patients had any evidence of proteinuria, red blood cell casts, or abnormality in renal function. As a consequence, it was felt by the referring physician that the patient might harbor significant underlying urologic disease, ie, either a bladder or a renal neoplasm.
The thrust of my study was to emphasize that I was unable to discover any urologic neoplasms either of the bladder or of the kidney. In essence, I was suggesting that an abbreviated urologic evaluation for female asymptomatic microhematuria might be considered that would