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Article |

Strongyloidiasis in an Institution for Mentally Retarded Adults

Todd I. Braun, MD; Thomas Fekete, MD; Annette Lynch, MD
Arch Intern Med. 1988;148(3):634-636. doi:10.1001/archinte.1988.00380030140024.
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• A serologic and epidemiologic survey was undertaken to explain the high incidence of eosinophilia (14.1%) In nine of 64 residents of a facility for mentally retarded adults in Pennsylvania. Seven residents had antibodies to Strongyloides stercoralis as determined by an IgG enzyme-linked immunosorbent assay system (10.9%) and five (71.4%) of this subset had persistent eosinophilia, suggesting a strong association. Sex, race, age, ward, degree of retardation, and medication were not associated with eosinophilia. Stool examination revealed S stercoralis larvae in two residents with S stercoralis antibodies and eosinophilia. Follow-up studies after thiabendazole treatment of the residents with S stercoralis antibodies showed resolution of eosinophilia and disappearance of S stercoralis antibodies in most. Eosinophilia in an adult institutional setting may be associated with strongyloidiasis, even in a nonendemic area. The enzyme-linked immunosorbent assay for antibody to S stercoralis may be useful in diagnosing or monitoring therapy of strongyloidiasis.

(Arch Intern Med 1988;148:634-636)


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