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Paroxysmal Nocturnal Hemoglobinuria Associated With the Acquired Immunodeficiency Syndrome

Michael A. Baumann, MD; Jaime Pacheco, MD; Cassandra C. Paul, PhD; Timothy Sorg, MD; Nosrat Hillman, MD
Arch Intern Med. 1988;148(1):212-213. doi:10.1001/archinte.1988.00380010214023.
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• Pancytopenia Is a well-recognized manifestation of clinical Illness related to human immunodeficiency virus infection. The mechanism of this has been debated, but has been thought to relate either to a nonspecific marrow suppressive effect of opportunistic infections, or to direct involvement of bone marrow hematopoietic precursors as a target of human immunodeficiency virus. We report the unique temporal association of the acquired immunodeficiency syndrome and paroxysmal nocturnal hemoglobinuria.

(Arch Intern Med 1988;148:212-213)


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