During the past 100 years, many of our learned neurologic colleagues have written or compiled textbooks of clinical neurology. Heretofore, such books provided us primarily with a classification and description of the clinical symptoms, signs, and (where possible) the gross and microscopic features of specific diseases of the nervous system. In the past 25 years, the field of clinical neurology has changed dramatically. The amount and sophistication of neuroscience research has increased enormously. Today, the neurologist is no longer simply a cataloger of syndromes, but a truly modern physician, one who applies the principles of neurobiology to his diagnostic and therapeutic approach to clinical neurology.
Until the publication of this textbook, as edited by Drs Asbury, McKhann, and McDonald, the house officer or practicing physician seeking knowledge about the neurobiological advances, or latest information on neurologic disease, was faced with a morass of complicated research articles, often appearing in unfamiliar