An Apparent Cluster of Aplastic Anemia: Credible Science?

Stanley H. Schuman, MD
Arch Intern Med. 1986;146(4):809. doi:10.1001/archinte.1986.00360160265043.
Text Size: A A A
Published online

To the Editor.  —Linet et al1 were puzzled by the occurrence of four cases of aplastic anemia occurring among teenagers in the rural community of Gaffney, SC, during the years 1973-1980.This led them to a search for some common exposure. Despite two retrospective interview studies, they came up empty-handed. Nevertheless, they report the details of their search to alert practitioners to the possibility of similar clusters.First reading of the article leads one to expect some hard data to support an association between cases and "employment in the textile industry and in agriculture (specifically peach orchards)." This was picked up by the Associated Press in a news story dated Sept 18, 1985.Careful reading of the article yields the following facts: (1) four cases are listed, two of which discuss brothers in a single household. One developed anemia at age 8 years and infectious mononucleosis two months prior


Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
First page PDF preview





Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.