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Cutaneous Manifestations of Sarcoidosis Relationships to Other Organ System Involvement, Abnormal Laboratory Measurements, and Disease Course

Kenneth E. Olive, MD; Yash P. Kataria, MD, FRCP, FCCP
Arch Intern Med. 1985;145(10):1811-1814. doi:10.1001/archinte.1985.00360100071011.
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• The charts of 329 patients with sarcoidosis were reviewed to determine if there were significant associations between the presence of sarcoidosis skin lesions and other abnormalities. Sixty-four patients had either biopsy specimen-documented cutaneous granulomata or erythema nodosum (EN). Respiratory symptoms occurred in 41% of patients with skin lesions compared with 63% of patients with sarcoidosis without skin lesions. Among patients with skin lesions other than EN, splenomegaly occurred in 38%, hepatomegaly in 32%, and lymphadenopathy in 31% compared with 10%, 11%, and 56%, respectively, for patients with sarcoidosis without skin lesions. Thirty-two percent of patients with EN had progressive disease compared with 72% of patients with skin lesions other than EN; however, improved prognosis with EN was limited to white patients.

(Arch Intern Med 1985;145:1811-1814)

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