0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

Magnesium Depletion as a Cause of Refractory Potassium Repletion

Robert Whang, MD; Edmund B. Flink, MD, PhD; Thomas Dyckner, MD; Per O. Wester, MD; Jerry K. Aikawa, MD; Michael P. Ryan, PhD
Arch Intern Med. 1985;145(9):1686-1689. doi:10.1001/archinte.1985.00360090162024.
Text Size: A A A
Published online

Because of the significance of potassium in the practice of medicine, it is important to consider factors that influence the integrity of intracellular and extracellular K. Clinicians today are skilled in managing hypokalemia as well as hyperkalemia. However, physicians may be less aware of the role of magnesium in K homeostasis.

Experimental observations to date support the view that Mg and K metabolism are closely linked. Dietary Mg depletion in the rat is accompanied by muscle K depletion, which occurs despite provision of K.1,2 Concurrent K and Mg depletion results in a greater loss of muscle K than with K depletion alone.3 In K- and Mg-deficient rats, muscle-cell K repletion is not optimized unless both K and Mg deficits are simultaneously corrected.4 Thus, Mg appears to be important not only in maintenance of cell K but also in conservation and repletion of cell K.5 These experimental

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();