—We thank Dr Norfleet for his useful comments, especially with regard to aspirin usage in older individuals with transient ischemic attacks. We agree that low dosage salicylates need not be interrupted during colorectal cancer screening. It is also interesting that only half of his patients with occult blood in their stools had complete follow-up examination; this figure is quite consistent with the findings in other studies. Finally, accurately estimating the cost of cancer screening is difficult. We suggest that third-party payers and prepaid groups should encourage screening by underwriting mass colorectal cancer testing, since a considerable saving of lives and money would likely be achieved.