Thyroid Needle Biopsy

J. Martin Miller, MD; Sudha R. Kini, MD; Joel I. Hamburger, MD
Arch Intern Med. 1985;145(4):764-765. doi:10.1001/archinte.1985.00360040204052.
Text Size: A A A
Published online

To the Editor.  —WE read with interest the experience of Ramacciotti et al1 in selecting patients for thyroid nodule surgery by fine-needle biopsy as well as the editorial comments of Blum.2 Both concluded that a test that identifies five of 19 papillary, two of two follicular, and one of four medullary carcinomas as "benign" was not reliable as a single diagnostic tool. We agree that these results justify such a conclusion. However, our somewhat larger experience from 1,005 nodule operations and 474 cases of cancer studied between 1976 and January 1984 permit a different conclusion. None of 20 medullary, only three of 297 papillary, and only two of 104 follicular carcinomas were diagnosed as benign by fine-needle biopsy. These false negatives were all from our first 500 satisfactory biopsies from a total experience of more than 4,000. Four of the five false negatives by fine needle were correctly


Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
First page PDF preview





Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.