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Disseminated Aspergillosis Complicating Hepatic Failure

Pascual Sesma, MD; Juan C. Alvarez, MD; Pedro Llinares, MD; M. Dolores Suarez, MD
Arch Intern Med. 1984;144(4):861. doi:10.1001/archinte.1984.00350160231045.
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To the Editor.  —In the June 1983 Archives, Walsh and Hamilton1 reported three cases of disseminated aspergillosis complicating hepatic failure. The patients in all three of these rare cases received corticosteroid treatment. We recently treated a case in which the only predisposing factors were cirrhosis and heavy drinking.

Report of a Case.  —A 32-year-old man was admitted to the hospital with a three-day history of Jaundice, fever, and obnubilation. He also had an abnormal chest roentgenogram. He had had a previous diagnosis of chronic sequelae of alcohol consumption 15 months before, and he continued to be a heavy drinker. Physical examination showed a temperature of 38.8 °C, icterus, spider nevi, flapping tremor, and confusion. Examination of the thorax disclosed scattered ronchi and basal rales. The patient's liver was palpable 8 cm below the right costal margin. The spleen was not felt and there were no ascites.Laboratory studies disclosed


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