Tumor Seeding Associated With Bone Marrow Aspiration and Biopsy

Marc L. Citron, MD; Steven H. Krasnow, MD; Cheryl Grant, RN; Martin H. Cohen, MD
Arch Intern Med. 1984;144(1):177. doi:10.1001/archinte.1984.00350130207038.
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• A 53-year-old man with small-cell lung carcinoma underwent bone marrow aspirations and biopsies for tumor staging and harvest for autologous bone marrow infusion. Fourteen months after bone marrow aspiration and biopsy, a subcutaneous lesion grew over the posterior iliac crest, and a biopsy specimen disclosed small-cell carcinoma. To our knowledge, this is the first case report of tumor seeding associated with bone marrow aspirate and biopsy.

(Arch Intern Med 1984;144:177)


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