Sequestered Substernal Goiter

Paul W. Ladenson, MD; Gordon C. Vineyard, MD; Geraldine S. Pinkus, MD; E. Chester Ridgway, MD
Arch Intern Med. 1983;143(5):1015-1017. doi:10.1001/archinte.1983.00350050179031.
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• A young woman with a normally located and only subtly nodular thyroid gland in the neck was found to have a clinically distinct and radioisotopically "cold" anterior mediastinal mass, which proved to be a benign colloid adenoma. While this constellation of findings usually suggests the presence of a nonthyroidal neoplasm, eg, lymphoma, thymoma, or teratoma, our case illustrates that sequestered benign nodular goiter should also be considered in the differential diagnosis. Clinical clues, such as a nodular thyroid gland, movement of the mass with deglutition, and a family history of nodular goiter, should suggest this possibility. A characteristic computed tomographic appearance may also prove useful in recognition of this rare disorder.

(Arch Intern Med 1983;143:1015-1017)


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