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Article |

Hepatitis and Jaundice Associated With Measles in Young Adults An Analysis of 65 Cases

Dov Gavish, MD; Yosef Kleinman, MD; Abraham Morag, MD; Tova Chajek-Shaul, MD
Arch Intern Med. 1983;143(4):674-677. doi:10.1001/archinte.1983.00350040064008.
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• We analyzed the clinical course of 65 adult patients hospitalized because of measles during the years 1975 and 1981-1982. Liver involvement was found in 80% (52/65) of the patients, five patients had clinical jaundice. The disturbances of liver function tests reached their peak values between days 5 and 10 of the disease. In this study of measles in adulthood we have three observations of unusual interest: (1) hepatitis occurs commonly in the more severely ill patients and it may manifest clinically as jaundice; (2) long-term follow-up (up to seven years) shows a clear tendency to complete resolution of the liver damage; (3) there is a clear correlation between the severity of hepatic involvement and the occurrence of secondary bacterial infections.

(Arch Intern Med 1983;143:674-677)


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