To the Editor.
—Spontaneous remission of hyperthyroidism and hypothyroidism following pregnancy has been associated with elevated levels of thyroid antimicrosomal antibodies during the time of altered thyroid function.1.2 A woman with transient hyperthyroidism during pregnancy was noted to have elevated thyroidstimulating immunoglobulin levels only when she was hyperthyroid, but negative antimicrosomal antibodies throughout her course.
Report of a Case.
— A 25-year-old woman was seen when she was three months pregnant. She had symptoms and signs of hyperthyroidism and a 50-g goiter. Past medical history was remarkable in that during each of her preceding three pregnancies she had noted a goiter and similar symptoms, all of which resolved after delivery.A suppression test with liothyronine sodium (Cytomel) resulted in an increase in serum thyroxine level from 15.6 to 19.5 μg/dL. She was given propranolol hydrochloride, 10 mg four times daily; this was continued until delivery of a normal infant