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Traumatic Cardiac Hemolytic Anemia A Late Complication of a Starr-Edwards Mitral Valve Prosthesis

Gary B. Weiss, MD, PhD; Arthur W. Nienhuis, MD; Charles L. McIntosh, MD, PhD; Harvey G. Klein, MD
Arch Intern Med. 1979;139(3):374-375. doi:10.1001/archinte.1979.03630400088032.
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Severe, traumatic, cardiac, hemolytic anemia developed in a patient nine years after mitral valve replacement with a Starr-Edwards model 6120 prosthesis. Cardiac catheterization failed to demonstrate a perivalvular leak or prosthetic malfunction. Transfusion on two occasions resulted in accelerated hemolysis and failed to maintain an appreciable elevation of the hemoglobin level. At operation, a perivalvular leak was found. Replacement of the valve led to complete resolution of the hemolytic problem. The case demonstrates that cardiac hemolysis may be a good indicator of valve dysfunction.

(Arch Intern Med 139:374-375, 1979)


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