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Primary Care Medicine

Arch Intern Med. 1978;138(6):899-900. doi:10.1001/archinte.1978.03630310001001.
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Seasonal variations in receptor levels  ?The amount of estrogen receptor protein in breast tumors—often considered helpful by physicians in assessing the probability that a patient will respond to hormonal therapy—may vary seasonally as much as tenfold, an organic chemist reported at an American Cancer Society meeting in Houston.Herbert I. Jacobson, PhD, says his data come from 1,200 breast cancer patients studied in upstate New York.If similar findings are substantiated for a larger geographic area, physicians someday may also consider the season when using hormone receptor levels as an index in decisions about the management of breast cancer.Dr Jacobsen says he believes "that the seasonal fluctuations in breast

Hemodialysis increase  By 1984, more than 55,000 persons in the United States will be receiving hemodialysis for chronic kidney disease. This National Institute of Arthritis, Metabolism and Digestive Diseases estimate is called "conservative" by the National Kidney Foundation.There are


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