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Trace Element Contamination of Intravenous Solution

Maurice Shils, MD, ScD
Arch Intern Med. 1977;137(7):965. doi:10.1001/archinte.1977.03630190105033.
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To the Editor.—  In their recent article in the Archives (136:782-784, 1976), Jetton et al provided additional information on the mineral composition of various intravenous solutions to supplement the growing information on this subject.These authors state that "the adult zinc dosage per day in the Shils et al formula is 10 mg of zinc." Neither my colleagues nor I have made this statement or provided data for such a statement either in the article to which they refer (N Engl J Med 283:341-344, 1970) or in any subsequent publication. In fact, our article states specifically that 1 ml of a traceelement solution per day was added to a 2-liter bag of solution; this provided 2.0 mg of zinc, as well as three other ions. I suspect that Jetton et al have uncritically accepted the erroneous statement made by Hull in their reference 7 without reviewing our original paper. The

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