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Gestational Trophoblastic Disease

Robert L. Becker, MD; Louis V. Avioli, MD
Arch Intern Med. 1977;137(2):221-225. doi:10.1001/archinte.1977.03630140069014.
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Wesley Murfin, MD, Assistant in Medicine, Department of Medicine, Jewish Hospital of St Louis, Washington University School of Medicine: A 20-year-old white female subject was in good health until September of this year. On Aug 24, 1975, she was delivered of a normal 3.15-kg baby vaginally, following an entirely normal pregnancy, and apparently normal immediate postpartum course. On Sept 4, ten days following delivery, she was seen in a hospital in Illinois complaining of the abrupt onset of pleuritic left-sided chest pain. A chest film initially showed nodular infiltrates in the upper lobe of the left lung. She was hospitalized and a second chest x-ray film several days later evidenced progression of the nodular infiltrates throughout both lung fields and a small left pleural effusion. Perfusion scan was normal. Results of sputum cultures, purified protein derivative (PPD), fungal skin tests, VDRL, and a "collagen vascular disease" screen were all unremarkable


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