Segmental Renin Sampling and Partial Nephrectomy in Renal Hypertension

Jan R. Stockigt, MD, FRACP; Nina Sacharias, MRACR, FRCR; Alex S. Wood, FRACS; Leslie M. Dugdale, MD, FRACR
Arch Intern Med. 1976;136(11):1297-1298. doi:10.1001/archinte.1976.03630110059015.
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Selective renin sampling from renal vein tributaries identified a high-renin source in the lower pole of the left kidney in a 16-year-old boy who had gradually developed hypertension after blunt left renal trauma. Localized renin secretion from the ischemic pole was associated with suppression of renin secretion from both the contralateral kidney and the normal part of the affected kidney. Removal of ischemic tissue by partial nephrectomy produced sustained correction of hypertension. The findings indicate that segmental renin sampling can define indications for partial nephrectomy in renal hypertension.

(Arch Intern Med 136:1297-1298, 1976)


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