Bone-marrow scintigraphy with indium chloride In 111 was performed on a patient with pure red blood cell aplasia before and after successful treatment with immunosuppressive drugs. The return of erythroid precursors to the bone marrow was accompanied by a substantial increase in the marrow uptake of111In. The distribution of111In in the posttreatment scan was indistinguishable from that of52Fe. These results indicate that indium chloride In 111 is a useful agent for the delineation of erythroid cellularity within bone marrow.
(Arch Intern Med 136:1169-1172, 1976)