A patient with Kaposi sarcoma showed increased uptake of sodium pertechnetate Tc 99m over both clinically evident and occult regions of involvement. The clinically negative but scanpositive regions showed pathologic lesions by biopsy. Gallium citrate Ga 67 and bleomycin sulfate labeled with indium 111 (111In) did not concentrate in the lesions, which suggests that Kaposi sarcoma, despite its resemblance to lymphoma, differs from lymphoma substantially with reference to radionuclide uptake. This report confirms that sodium pertechnetate Tc 99m is the most sensitive agent for diagnostic and therapeutic evaluation of patients with Kaposi sarcoma and suggests that gallium citrate Ga 67 or bleomycin111In may be useful in the differentiation of Kaposi sarcoma from lymphoma.
(Arch Intern Med 136:400-403, 1976)