This book consists primarily of fulllength research papers presented at a symposium held in Philadelphia in Jaunuary 1973, on the mechanism of action of steroids and their possible application to the treatment of various types of shock. These papers are by basic scientists and research clinicians. They document basic pharmacological and physiological action of the various steroids and define, in a scientific way, their effects on intracellular, extracellular, and circulatory processes, both in the normal and the shock state. These findings are discussed and interpreted by several international authorities in the field of shock.
Although a tremendous amount of information is made available on the action and usefulness of steroids in shock, it is a measure of the objectivity of a summarizing author that he concludes "regarding the use of corticosteroids as an adjunct to the treatment of shock states... neither malpractice to do so nor negligence if you elect