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Lupus Erythematosus

Bevra H. Hahn, MD; Louis V. Avioli, MD
Arch Intern Med. 1975;135(12):1617-1621. doi:10.1001/archinte.1975.00330120095015.
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DENNY Guletz, MD, Junior Assistant Resident in Medicine, Jewish Hospital of St. Louis, and Instructor in Medicine, Washington University School of Medicine: A 25-year-old woman was admitted to the Jewish Hospital for evaluation of a trance-like state. She had been in good health until several months prior to admission, when her private physician noted that she had a mild anemia that was resistant to iron therapy. Approximately three months before admission, the patient developed intermittent arthalgias and stiffness located mainly in her ankles, knees, hands, and elbows. The joints characteristically became warm, erythematous, and slightly swollen. In the two months prior to admission, a 9.1kg (20 lb) weight loss was recorded. One month before admission, the patient developed weakness and fatigue, and her husband noted she was listless and forgetful. She had several brief episodes of trance-like states, during which she would stare off into space, seemingly oblivious to her


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