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Living Blood Cells and Their Ultrastructure,

O'Neill Barrett Jr, MD
Arch Intern Med. 1975;135(10):1406. doi:10.1001/archinte.1975.00330100132023.
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Morphologists rejoice! Several hematology texts have become available recently, but none have been devoted exclusively to morphology, a relatively neglected area. Now there are two texts and an elegant atlas on red blood cells just for "langiappe."

The most exciting of these is Living Blood Cells and Their Ultrastructure by Bessis. In his usual thorough manner, the author has presented the story of normal and abnormal blood cells, by a combined morphologic and pathophysiologic approach. In addition to standard light microscopy, the story is developed with a careful blend of phase microscopy, scanning electron microscopy (SEM), electron microscopy, and exquisite line drawings.

While the average clinical hematologist will not have SEM or electron microscopy routinely available, these techniques will help him understand and even "see" things that he knows are there but that are just beyond view with the standard microscope and routine blood smear. One of the startling aspects


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