Larry Young has inspired a whole 1 generation of clinical investigators, initially through his own outstanding scientific contributions and then through his leadership of the Department of Medicine at the University of Rochester School of Medicine and Dentistry. He has always maintained the importance of relating basic investigation to patient care. It is noteworthy that basic advances in our understanding of neuroendocrine relationships, as exemplified by Dr. Reichlin's elegant studies, have greatly facilitated the care of patients with endocrine disease. Indeed, the foundation for much of Dr. Reichlin's current work was developed during his tenure as head of the endocrinology unit in Larry Young's department.
I would like to illustrate the physiological and clinical importance of certain recent advances in neuroendocrinology and speculate about the possible impact of nascent work in the field.
The hypothalamus is a major regulator of anterior pituitary function and, therefore, an important link between