Almost ten years have gone by since DuBois first published his splendid text on lupus erythematosus. The second edition is a welcome one since so many changes concerning the disease have occurred during the past decade. The book has been updated primarily through the use of supplements to chapters rather than incorporation of that material into the body of the original text. This makes the book a bit more ponderous and cumbersome to use but in no way detracts from the value of the book. The new section on the immunologic phenomena in the disease is especially valuable. The references have doubled and number almost 3,000. The book is encyclopedic in scope and remains the standard reference for lupus erythematosus.