To the Editor.—

S. Raymond Gambino, MD; Kenneth F. Button, MD; Robert S. Galen, MD, MPH
Arch Intern Med. 1975;135(4):623-624. doi:10.1001/archinte.1975.00330040135027.
Text Size: A A A
Published online


Dr. Laszlo's editorial on "Automated 'Chemistries'" (Arch Intern Med 133:1068-1069, 1974) is a mixture of truth, half-truth, and fiction. He is correct to question the cost-effectiveness of automatic ordering of automated laboratory screening, and he is correct when he doubts the rationality of performing tests simply because they can be done automatically. But little else in his editorial is correct.

Dr. Laszlo, for example, is misinformed regarding many technical matters. A nonuricase method for uric acid is not necessarily a poor method. Lum and Gambino (Clin Chem 19:1184-1186,1973) studied four methods for uric acid and found the SMA 12/60 colorimetric method to more precise than a manual uricase method and to be almost as accurate as an automated kinetic uricase method. Ultraviolet enzyme assays are not automatically superior to colorimetric assays. Furthermore, he is unaware that levels of serum glutamic oxaloacetic transaminase (SGOT) and lactic acid dehydrogenase (LDH) are now


Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
First page PDF preview





Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.