During the past several years, in a study of the cutaneous arterial "spiders"† which may occur in certain persons with liver disease, pregnancy, and nutritional deficiency disorders, and in apparently normal persons, observations have been made on two hundred fifty-one subjects.1 These have been followed for periods varying from a few days to five years. Among the associated vascular phenomena, a curious hyperemia of the skin of the palms and sometimes of the soles has been encountered in a few instances.‡ This appears to have an important relation to vascular spiders. A review of the reports of similar cases has been undertaken, and personal observations on eleven new ones will be presented.
In surveying the literature one encounters great difficulty in deciding whether to include certain obscure conditions of the palms and soles among the cases here considered. Reports during the last quarter of the nineteenth century were often vague about