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Mitral Valve Obstruction and Pulmonary Congestion Due to Malignant Mesothelioma

John Olds, MD; James Langley III, MS; William Black, MD; Richard D. Lueker, MD
Arch Intern Med. 1974;134(1):142-144. doi:10.1001/archinte.1974.00320190144024.
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Metastatic tumors involve the heart infrequently. Of those that do, usual sources are bronchogenic carcinoma, malignant lymphoma, breast carcinoma, and malignant melanoma. Malignant mesotheliomas only rarely involve the heart, either as primary tumors or metastatic foci, and most of these occur in the pericardium.1,2 To our knowledge, this is the first reported case of pleural malignant mesothelioma extending through a pulmonary vein and into the left ventricle to produce ball valve obstruction of the mitral valve.

Patient Summary  A 63-year-old white woman was referred to the Bernalillo County Medical Center on Nov 25,1969, for evaluation of a lung mass discovered by chest roentgenography. She had been well until 1961 when she was first hospitalized in diabetic coma. Her condition was subsequently adequately controlled by diet, insulin, or orally administered hypoglycemic agents. In the fall of 1969, she was admitted to another hospital with a urinary tract infection, at which


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