We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Booster Immunization Against Rubella in Adult Women

Te-Wen Chang, MD; Suzanne DesRosDesRosier ,; Louis Weinstein, MD
Arch Intern Med. 1973;131(4):530-531. doi:10.1001/archinte.1973.00320100058006.
Text Size: A A A
Published online


Twenty-three seronegative women living in a mental institution were immunized with Cendehill rubella vaccine. Five others without antibody to rubella who resided in the same quarters were not immunized and served to monitor the possible introduction of wild virus into the institution. All those who received the vaccine developed significant antibody titers. Nine months following the initial vaccination, ten women were given a booster dose of vaccine; none showed an increase in antibody titers. Twenty-two months after primary immunization, the other 13 were reimmunized; only one exhibited a response. The incidence of a booster effect for the group as a whole was only 4.4%. None of the unvaccinated seronegative individuals developed specific antibody, indicating a lack of introduction of wild rubella virus into the environment.


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.