Electrocardiographic Effects of Glucose Ingestion

Charles Parker Riley, MD; Albert Oberman, MD, MPH; L. Thomas Sheffield, MD
Arch Intern Med. 1972;130(5):703-707. doi:10.1001/archinte.1972.03650050031005.
Text Size: A A A
Published online

To assess the influence of glucose ingestion on resting and exercise electrocardiograms, 35 subjects were tested after ingestion of a glucose solution and a placebo on separate days. Graded submaximal exercise tests (GXTs) were performed to 90% predicted maximal heart rate. Computer-processed ECGs taken at rest showed a decrease in T-wave amplitude, more ST-segment depression, increased R-wave amplitude, and increased heart rate after glucose. Minnesota code classifications of these same ECGs were more abnormal after glucose. Computer-processed exercise ECGs showed a decrease in T-wave area after glucose ingestion during and after exercise. ST-segment area showed the most variability at one minute after exercise. Three subjects had normal exercise ECGs after placebo and abnormal ECGs after glucose ingestion (ST area >7.5μv/sec). Both resting and exercise ECGs should be made fasting to avoid this significant source of variability.


Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours





Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.