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Small Bowel Perforation in Regional Enteritis Resulting From Adenocarcinoma

Ivan Mauer, MD; Harry Miller, MD; Ruven Levitan, MD
Arch Intern Med. 1972;130(2):275-276. doi:10.1001/archinte.1972.03650020095017.
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Since the first report in 1956 by Ginsburg and associates1 of adenocarcinoma of the small intestine occurring in patients with regional enteritis, a total of 21 similar cases have been reported.2-5 None of these patients perforated their bowel.

Free small bowel perforation in the course of regional enteritis, in general, is a rare event.4,6 In none of these patients did the small bowel perforation result from a tumor.

Since evidence regarding the association of regional enteritis and carcinoma seems to be emerging1-5 and small bowel perforation in the course of regional enteritis4,6-10 is a rare complication, we wish to report a patient in whom adenocarcinoma of the small bowel resulted in a free small bowel perforation after 24 years of regional enteritis.

Patient Summary  A 43-year-old white woman was admitted for the first time on July 20,1968, to the New England Medical Center Hospitals (195-961).


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