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Iron Deficiency Anemia, Papilledema, Thrombocytosis, and Transient Hemiparesis

Homer Knizley Jr, MD; Ward D. Noyes, MD
Arch Intern Med. 1972;129(3):483-486. doi:10.1001/archinte.1972.00320030103013.
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The signs and symptoms found in iron deficiency anemia are nu merous and diverse, but the morbid ity is usually mild. However, several manifestations if wrongly diagnosed and incorrectly treated can lead to serious consequences. Papilledema as sociated with iron deficiency is a known but rare phenomenon which may so alarm the physician as to pro voke extensive and needless eval uations for intracranial lesions. Other associated neurological defects pre viously reported have usually been minimal but when present arouse an even higher suspicion of a space-oc cupying mass. Thrombocytosis is fre quently seen in adults with iron deficiency, but it is sufficiently unrecognized that patients may be thought to have a myeloproliferative disease with insufficient consid eration to iron as an etiological mech anism. We wish to emphasize through the following patient summary the reversible nature of these complications by the simple and oral administration of iron.


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