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Cardiac Performance Three to Eight Weeks After Acute Myocardial Infarction

Shahbudin H. Rahimtoola, MB, MRCPE; Michael M. DiGilio, MD; M. Ziad Sinno, MD; Henry S. Loeb, MD; Kenneth M. Rosen, MD; Rolf M. Gunnar, MS, MD
Arch Intern Med. 1971;128(2):220-228. doi:10.1001/archinte.1971.00310200056004.
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When cardiac performance was assessed three to eight weeks after uncomplicated acute myocardial infarction (AMI) in patients not in clinical cardiac failure, abnormalities of left ventricular (LV) function were demonstrated in 22 of 27 patients who, by clinical criteria, were recovering satisfactorily. Left ventricular end-diastolic pressure (LVEDP) was measured in 24 patients. It was elevated in 19, ranged from 14 to 20 mm Hg in 13, and was > 20 mm Hg in 6. Patients comprised three groups: group 1—5 patients with normal LVEDP, cardiac index (CI), stroke index (SI), and preejection period (PEP) to left ventricular ejection time (PEP/LVET) ratio; group 2—12 patients with elevated LVEDP (14 to 24 mm Hg) but normal CI, SI, and PEP/LVET ratio and; group 3—10 patients with elevated LVEDP (14 to 30 mm Hg), reduced CI and SI ( < 2.5 liters/min/sq m and < 30 ml/sq m), and increased PEP/LVET ratios ( > 0.381).


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The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
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