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Ultrastructural Aspects of the Liver and its Disorders.

Frank L. Iber, MD
Arch Intern Med. 1971;127(5):965-966. doi:10.1001/archinte.1971.00310170173033.
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Tanikawa is a liver clinician spending about half his time seeing clinical problems and the rest in investigation; electron microscopy (EM) is one of his tools. As a result of his clinical interest he has produced an extremely usable monograph on the value of electron microscopy of the liver. More than half of the book consists of full-page micrographs, each with legends that enhance and teach. A few schematic line drawings clarify dynamic phenomenon.

Normal liver histology and physiology make up about one third of the book. Thus, the movement of particulate matter from the space of Disse into the liver cell and from bile duct lumen back into perilymphatic spaces is clearly shown. Common and uncommon pathological states are covered with proper emphasis from the clinical point of view on differential diagnosis. Many points are demonstrated convincingly in the photographs that I had found previously only alluded to in


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