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Cardiovascular and Coagulation Complications of Group C Meningococcal Disease

Thomas C. Denmark, MC; E. Larry Knight, MC
Arch Intern Med. 1971;127(2):238-240. doi:10.1001/archinte.1971.00310140066006.
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Ten consecutive patients with group C meningococcal infection and their treatment at Kessler (Miss) Air Force Base during the winter of 1968 to 1969 form the basis of this report. Eight had Neisseria meningitidis isolated from the blood while six had meningitis proved by culture. Although disseminated intravascular coagulation, hypotension, and congestive heart failure were frequent complications, all patients survived. Disseminated intravascular coagulation with hypotension occurred in three patients, two of whom were treated with heparin sodium. Congestive heart failure occurred in seven cases, and central venous pressure monitoring aided in the early recognition of this complication. Our experience demonstrated that early diagnosis and rapid treatment of the complications with emphasis on early digitalization and fluid restriction may be rewarding.


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The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
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