The first edition of this delightful little book was published in 1966. Since then it was reprinted, translated into German, and now the second edition has been published. The book grew from 129 to 172 pages and 12 new figures have been added. The author carefully reviewed every page, changed old chapters, and added new ones.
In spite of its growth, it retains the qualities which made it so successful. These are the author's excellent knowledge of both pediatrics and cytogenetics, combined with the gift of storytelling. Valentine can transform scientific facts and clinical observations into a highly entertaining, amusing "story-book," as he calls it. The conversational style is reminiscent of William Boyd's fine texts on pathology. The autosomal chromosome abnormalities are coupled with the corresponding clinical features. Mongolism, with its different types (antimongolism, inherited, and dinovo translocation mongols, regular mongolism) are described with advice for the management of the