The present book is the third section of the 14th volume of the Handbook of Experimental Pharmacology, a monumental multivolume compendium critically reviewing the status of each subject, up until the time the section was written. Because of the exigencies of publishing a multiauthored work that represents an exhaustive compilation of the international literature, the effectiveness of this approach is somewhat narrowed. The various sections review the literature to March 1964; 1964; 1967; and 1965, while the doubling time for scientific literature is surely less than ten years. Since this obviates the possibility of arriving at the present status of knowledge from this volume, it is evidently intended to provide a carefully constructed foundation upon which the current literature can safely be built.
Especially noteworthy in this compendium is the lucidly written section on glucocorticoids by Janoski, Shaver, Christy, and Rosner and a chapter on the control of aldosterone secretion