Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Pancreatic Insufficiency and Neutropenia With Associated Immunoglobulin Deficit

Edsel Hudson, MD; Thomas Aldor, MB, BS, MRACP
Arch Intern Med. 1970;125(2):314-316. doi:10.1001/archinte.1970.00310020120017.
Text Size: A A A
Published online


Recent reports have called attention to the association of pancreatic insufficiency and bone marrow dysfunction in children.1-7 This syndrome, although uncommon, is thought to represent the major disorder of pancreatic dysfunction in childhood when cystic fibrosis is excluded. We have recently evaluated such a patient in whom the significance of the association was not realized until adolescence and who was also found to have immunoglobulin deficiencies.

Patient Summary  A 16-year-old white boy was admitted to the hospital in 1966 for evaluation of previously diagnosed pancreatic insufficiency. He was born at eight months' gestation and weighed 3,281 gm (5 lb 4 oz). His first teeth appeared when he was 7 months old and he walked at 21 months of age. The patient was thought to have celiac disease during his first year when he was found to be anemic and to have bulky, foul-smelling stools. It was also reported that


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.