Lingual fungiform papillae were absent or scanty in eight and significantly reduced in three out of 13 patients with the characteristic features of Behcet's syndrome. Examination was made by slit-lamp or by eye microscope. The finding is not pathognomonic. It is seen in the Riley-Day syndrome and has also been seen in 8 of 150 varied medical outpatients but in none of 40 healthy persons. Fungiform papillae were plentiful in six patients with severe aphthous stomatitis, and in five patients with uveitis only.