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Round Table Discussion

Arch Intern Med. 1969;124(6):670-682. doi:10.1001/archinte.1969.00300220022004.
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Calcitonin  Louis G. Welt, MD, Professor and Chairman, Department of Medicine, University of North Carolina School of Medicine, Chapel Hill: There have been a number of allusions in a peripheral way to calcitonin (thyrocalcitonin) but really no substantive discussion of the possible role it might play throughout the course of chronic renal insufficiency, hemodialysis, and/or transplantation. Dr. Potts, would you speculate as to the role that calcitonin might be playing?John T. Potts, Jr., MD, Chief, Endocrine Unit, Massachusetts General Hospital, Boston: With respect to calcitonin, it would be appropriate to make several points.Figure 1 illustrates the structure of the porcine hormone which our group, as well as several others, worked out last year (Proc Nat Acad Sci USA59:1321, 1968; J Amer Chem Soc90:2704, 1968; and Helv Chim Acta51:917, 1968). The hormone has a tyrosine residue which makes it suitable for radioactive labeling


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